Bacteriology of normal non-Inflamed sinuses and its significance

Attempts to recover organisms from non-inflamed tonsils were carried out for over seven decades. Some studies failed to find any microorganisms and others recovered them only in a portion of the cases. Only three studies identified bacteria in all sinus sample. Brook evaluated the microbiology of maxillary sinuses of 12 adults and found an average of 4 isolates/sinus of aerobic and anaerobic bacteria. The predominant anaerobes were Prevotella Fusobacterium ,and Peptostreptococcus spp., and Propionibactreium acnes . The most common aerobic bacteria were beta-hemolytic Streptococcoci, Staphylococcus aureus , Streptococcus pneumoniae , and Haemophillus parainfluenzae . Ramakrishnanet al. collected middle meatus specimens from 28 individuals with no sinusitis. Bacterial colonization was assessed in these specimens using quantitative PCR and 16S rRNA pyrosequencing. All subjects were positive for bacterial colonization of the middle meatus. S. aureus, S. epidermidis and ...